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Volume 25(2), Summer 2015

Reprint paper

Blood clotting tests


Laboratory evaluation and interpretation

of haemostasis in small animals

by Reinhard Mischke

Primary or secondary?


Mucosal and cutaneous petechiae, purpura and ecchymoses are characteristic findings in disorders of primary - i.e. platelet-derived - haemostasis (thrombocytopenia, thrombocytopathia).

In contrast, disorders of blood coagulation ...

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Bleeders: Differential diagnosis

This review deals with indications for performing haemostasis tests, methodical aspects of blood sampling and handling of sample material, selection of appropriate tests and basic principles of test interpretation.

Indications for laboratory evaluation of haemostasis in small animals include spontaneous bleeding or bleeding disproportionate to the degree of trauma, bleeding from multiple sites and diseases which are frequently associated with haemostatic disorders. Patient history and clinical findings can provide clues to the type of haemorrhagic diathesis. Important pre-analytical issues include: prevention of prolonged venous stasis, order of drawing and appropriate filling of the collection tubes and careful mixing of blood with anticoagulant.

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