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Volume 24(2), Summer 2014

Reprint paper (BSAVA)

Corneal grafts

Use of porcine small intestinal submucosa for corneal reconstruction in dogs and cats: 106 cases

by Frédéric Goulle


Clinical findings and postoperative results of SIS graft surgery on 60 dogs and 42 cats with corneal defects.

SIS biomaterial

Small intestinal submucosa (SIS) is a non-immunogenic biomaterial capable of acting as a scaffold for tissue regeneration in different organs, including the eye. The biomaterial is composed of an acellular collagen matrix that acts as a medium for corneal remodelling and reconstruction.

Before and after


Click on any eye to see a short description and postoperative evolution of the case...


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Melting ulcers

SIS biomaterial appears particularly indicated for the surgical treatment of melting corneal ulcers.

Objectives: To describe the efficacy of porcine small intestinal submucosa in corneal reconstructive surgery in dogs and cats through a large retrospective study.

Methods: A retrospective evaluation of 106 cases of surgical reconstruction of the cornea with small intestinal submucosa seen between May 2005 and January 2010 was carried out. The corneal defect was filled by microsurgical grafting of porcine small ...

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