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Volume 24(1), Spring 2014

Reprint paper (HMVS)

Forms of MUE

This table provides an overview of the forms of meningoencephaliomyelitis of unknown aetiology (MUE), as discussed in the paper.


In contrast to most other forms of MEM of unknown origin, which are more common in small breeds, steroid-responsive meningitis-arteritis usually affects medium to large breeds of dogs. Breeds with an increased risk for developing the disease include Beagles, Boxers, Weimaraners, Bernese Mountain Dogs and Nova Scotia Duck-Tolling Retrievers.

Not only in small dogs


Brain pains

An update on meningoencephalomyelitis

of unknown aetiology in dogs

by Marios Charalambous, Tasos Danourdis, Aristodimos Hatzis, Zoe Polizopoulou

MUE: variable signs

The clinical signs in meningo-encaphalomyelitis of unknown aetiology (MUE) are variable and depend on the area of the central nervous system that is affected. Click here to see a Yorkshire terrier with MUE showing severe vestibular signs.

Inflammatory diseases of the central nervous system are common causes of neurological dysfunction in the dog and can be grouped into two broad categories; those of infectious and those of unknown aetiology. Meningoencephalomyelitis (MEM) of unknown aetiology describes a group of non-infectious inflammatory diseases of the central nervous system in which abnormal findings on magnetic resonance imaging and cerebrospinal fluid analysis indicate inflammatory central nervous system disease, but for which ...

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